Bioclinic Naturals Bromelain 500mg, 90 Capsules

Benefits

Provides 500 mg of bromelain from pineapple stems per capsule
Supports healthy digestion by enhancing the breakdown of dietary proteins
Provides the clinical dose used in controlled trials for supporting musculoskeletal health
Bromelain is well-absorbed and retains enzymatic activity, allowing for systematic anti-inflammatory effects

Feature Summary

Bromelain, found in pineapple stems, is a combination of multiple proteolytic enzymes classified as cysteine or thiol proteinases. Bromelain’s long history as a digestive aid is partly attributed to its protein-digesting ability over a wide pH range. However, it has also been shown to stimulate pancreatic enzyme production and improve epithelial integrity in experimental models.1,2

In addition to its function as a digestive enzyme, bromelain has been shown to be absorbed in the digestive tract and retain its enzymatic activity in the blood.3 Among its many enzymatic effects, bromelain has been shown to be a potent anti-inflammatory agent, reducing levels of inflammatory signals, such as tumour necrosis factor (TNF) and nuclear factor-kappa B (NF-kappaB).4–6

Bromelain’s anti-inflammatory, fibrinolytic, and analgesic effects mediate many of its musculoskeletal benefits as well. In an open-label trial, bromelain supplementation was shown to reduce acute knee pain as well as stiffness and function, with a dose-dependent effect.7 In another clinical trial of mild/moderate knee osteoarthritis, bromelain had similar efficacy to standard therapy at four weeks. By 16 weeks, improvements in pain, stiffness, and function were observed with bromelain supplementation.8 More rapid recovery and reduction of pain and swelling following multiple types of minor trauma have been reported with bromelain as well.9–11

Each Capsule Contains:
Bromelain (Ananas comosus var. comosus) (stem) .........................................................................7,500,000 FCC PU (500 mg)
Non-medicinal Ingredients: Gelatin capsule (gelatin, purified water), vegetable grade magnesium stearate (lubricant).

Recommended Adult Dose: 1 capsule per day with food or as directed by a health care practitioner. Consult a health care
practitioner for prolonged use.

Recommended Use: Digestive enzyme. Used in herbal medicine to help relieve minor pain, swelling, and inflammation.